A Cura e prevenção ocorrem por terapia natural. Suplementação de vitaminas, dieta alimentar

Vitamina D – Sem Censura – Dr. Cicero Galli Coimbra e Daniel Cunha em junho de 2012

http://www.youtube.com/watch?v=cIwIWim4hNM&list=UU5grjCGNi25VAR8J0eVuxVQ&index=4&feature=plcp

As células-tronco de embriões nunca foram necessárias para “curar”. Esta foi a grande mentira milionária de uma Medicina meramente comercial, industria farmaceutica e laboratórios multinacionais e clínicas – inclusive abortistas.

por Cristiane Rozicki

Os tecidos de fetos ou embrioes são usados em várias indústrias, desde as cosméticas, passando pelas de plásticas, até de medicamentos e transplantes, as injeções de células-tronco.

 

Solo le pido a Dios
Que el dolor no me sea indiferente.

 

A Cura e prevenção ocorrem por terapia  natural. Suplementação de vitaminas, dieta alimentar. O estado metabólico, depressão, alimentação e outros dados relativos á neurodegeneração.

 

 

  1. Durante muito tempo, na história da e.m., ouviu-se teses de que era doença geneticamente transmissível, ou que a esclerose múltipla poderia ser causada por um vírus, ou, ainda, que o vírus que levava ao desenvolvimento da esclerose múltipla estaria relacionado e advinha de epidemias tais como o sarampo e a catapora, ambas graves e infecciosas. Muitas dúvidas sem respostas que causavam verdadeiro estresse emocional aos doentes, uma aflição, por não se saber o que pensar e nem como agir.

  1. Alguns médicos até advertiam da necessidade do uso de vitaminas do complexo B, e outra medicação cara, valores altos em dinheiro.

  1. A esclerose múltipla é doença antiga, fim de 1800 ou início de 1900 quando surgiu notícia. Eram projetadas vacinas, um tema recente. Em mais ou menos 1995, uma vacina com células de porcos, assim como também existiu a idéia (que foi colocada em prática) de que pessoas com males do sistema nervoso central deveriam passar por terapias com choques elétricos (médicos nazistas também trabalharam com eletricidade). Já se viu de tudo. Choques elétricos foi passagem familiar. E, por fim, até a teoria de um tumor no encéfalo. Apenas na dec. de 90 surgiu a ressonância magnética. Com o diagnóstico de esclerose múltipla pararam de investir na idéia de que o mal neurológico era meramente psicológico. Mas, depois disso tudo, vingou a idéia de doença auto-imune. Daí os imunosupressores, interferon e rebif.

  1. Sofrimento emocional. Agonia mental que dizem deve-se disciplinar para não atingir o físico. Disciplinar o sofrimento parece impossível realizar. Claro que o físico acaba sendo atingido.

  1. Alimentação passou a ser difícil. Desde 1990 era possível perceber como alguns alimentos proporcionavam mal-estares tais como cansaço, fadiga, diminuição da mobilidade e alergias aparentes na pele. O pior era a carne vermelha, açúcar, adoçantes, bebidas artificiais, álcool, frituras e gorduras de origem animal e agora até o café.

  1. No entanto, desde 2003 com certeza,  já se sabe que doenças neurodegenerativas, e.m., assim como o mal de Parkinson, não são doenças transmissíveis e não são causadas por vírus. Na verdade, trata-se de algo simples e de fácil solução. A neurodegeneração é  resultado de distúrbio metabólico.

  1. Há meio de prevenir a degeneração do sistema nervoso central: basta exame de dosagem de vitaminas do complexo B no sangue, a Riboflavina, por exemplo – no caso da doença de Parkinson, e a eliminação de outros fatores desencadeantes das doenças: evitar o desgaste emocional e eliminar da dieta alimentar a carne vermelha.

Referencias:

Dieta livre de carne e rica em vitamina B2.

COIMBRA, CÍCERO GALLI.  Phd., Médico Neurologista e Professor Livre-Docente. Departamento de Neurologia e Neurocirurgia – Universidade Federal de São Paulo – Unifesp/EPM.

Dieta livre de carne e rica em vitamina B2 pode regredir Parkinson. Neurologia – Jornal da Paulista – ano 16 – n. 179 – Maio/2003.
http://www.unifesp.br/comunicacao/jpta/ed179/pesquisa4.htm

“Dieta livre de carne e rica em vitamina B2 pode regredir Parkinson. Estudo revela que portadores da doença apresentam deficiência da vitamina e ingerem muita carne vermelha; nova dieta fez com que a recuperação média motora dos pacientes saltasse de 44% para 70% em apenas três meses de tratamento”.

A “[…] situação fundamental é a mesma: a existência de um distúrbio metabólico evidente e corrigível, capaz de explicar os eventos fisiopatológicos conhecidos, e cuja correção pode deter a progressão da doença (interrompendo a continuidade da morte neuronal crônica, recuperando células neuronais já afetadas pelo processo neurodegenerativo – mas que não atingiram ainda o ponto de irreversibilidade), promover a recuperação total em casos de início recente, ou ao menos parcial das deficiências neurológicas nos casos mais avançados (minimizando seqüelas permanentes) e impedir a morte […]”.

Disponível em: http://www.unifesp.br/dneuro/nexp/riboflavina/c.htm

Parkinson – riboflavin and the elimination of dietary red meat promote the recovery

Abstract:
“Abnormal riboflavin status in the absence of a dietary deficiency was detected in 31 consecutive outpatients with Parkinson’s disease (PD), while the classical determinants of homocysteine levels (B6, folic acid, and B12)… received riboflavin orally (30 mg)”.
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001000019&lng=pt&nrm=iso
Brazilian Journal of Medical and Biological Research
ISSN 0100-879X. COIMBRA e JUNQUEIRA.

How a 52-year-old Parkinson’s Disease Sufferer and Naturopath Banished all the Frustrating Symptoms of this Cruel Condition from his Body.  Naturally!

John Coleman’s Video

disponível em

http://www.parkinsonsrecoveryprogram.com/parkinsonsrecoveryprogram.html

O texto fala sobre o fim do estresse, a mudança de alimentação, e nutrientes, mudança total do estilo de vida, para a recuperação da doença. A neurodegeneração tratada é Parkinson. Stop Parkin and Start Living. A página tem 2 vídeos.

http://www.parkinsonsrecovery.com/startliving/

From: Robert Rodgers, Ph.D.
Sent: Friday, July 11, 2008 8:16 PM
Subject: Vitamin and Mineral Deficiencies in the Body

Parkinsons Recovery
Vitamin and Mineral Deficiencies in the Body

There is a compelling reason why you may not be
feeling as energetic as you would prefer. That reason
simply put is that your body is not getting the nutrition that it needs to be fully functional.

Why is this the case, particularly if you are the kind
of person who eats healthy food? We do not get some of the vitamins and minerals our bodies need
to function well from the food we eat.

Production systems for food have changed dramatically over the last several decades. Processing of food strips out some of the minerals and vitamines our body needs the most. What our body needs to function well is not necessarily available in the food sold at grocery stores. Let me give you a few examples.

The first is Vitamin D3. Vitamin D3 is actually what you get when you get sunshine. The effects of sunshine last about 2-3 months. In the wintertime – particularly for those of us that live in the Northwest –  we can easily get depressed.

The reason is that our bodies are deficient in the vitamin created by sunshine. Under such circumstances our body needs more Vitamin D3 which (as it turns out) is actually available at pharmacies.

A second common deficiency in food is Iodine (or salt). Interestingly enough, foods don’t have enough Iodine in order for our bodies to perform their basic tasks. Deborah and I are currently taking supplement of Iodoral which is an Iodine Potassium supplement.

Third, we know that a reason why people are often fatigued is because of an overall deficiency in minerals and specifically magnesium. Many diseases are actually related to mineral or vitamin deficiencies. Health food stores have a variety of mineral and vitamin supplements to evaluate for potential use.

Consider the possibility of testing your body to assess any deficiencies that might exist in your body. After getting the results, make it a point to work with your doctor to bolster up your deficiencies so that your body can return to full health and wellness.”

 

Robert Rodgers, Ph.D.
Parkinsons Recovery
© 2008 Parkinsons Recovery
Zero Point Healers, 7722 Cooper Point Rd NW, Olympia, WA 98502, USA
http://www.aweber.com/z/r/?rMxMTCwstCxMjCycrGzstGa0jCyMLMwMbA

 

  1. Distúrbios Metabólicos, Estresse Emocional, Nutrientes. Neurogénese. A evolução da doença degenerativa sem os cuidados necessários pode fazer uma realidade assustadora em poucos anos de vida.

A Ciência e a medicina sabem que o corpo humano cria todos os dias neurônios e células-tronco. É verdade, acontece a neurogênese. A neurogenese permite a juventude e regeneração sonhadas. De um modo muito natural, a preservação do corpo humano e do cérebro acontecem. Os artigos são científicos e médicos, e estes trabalhos estão à livre disposição de qualquer leitor da internet, pode-se ver.

8.1. VIVA SAÚDE.  O estresse e o mal de Parkinson
Um novíssimo estudo aponta que a tensão emocional influencia no desenvolvimento dessa doença neurológica, que afeta os movimentos e causa tremores no corpo

http://revistavivasaude.uol.com.br/Edicoes/11/artigo5894-1.asp

8.2. A fadiga pode ser agravada não apenas pelo curso da Esclerose Múltipla propriamente, mas pela depressão, ingestão de alimentos pesados, elevação de temperatura. A depressão pode conduzir você ao afastamento de atividades recompensantes e conduzi-lo a escassos contatos sociais com amigos, levando-o a reduzir suas atividades físicas e seu bem estar.

Esclerose Múltipla – Karla Adryana Diniz Meireles

Em: http://www.geocities.com/doug_unesp/esclero.htm

8.3. ASPECTO NUTRICIONAL: SUPLEMENTO ALIMENTAR. Sítio canadense de e.m. – DIRIGIR-MS Estratégias ES.

Sítio canadense de e.m.
Fatores nutricionais e esclerose múltipla.
Nutritional Factors and Multiple Sclerosis
http://www.direct-ms.org/

GENERAL INFORMATION FOR EVALUATING SUPPLEMENTS

National MS Society | Brochure: Vitamins
http://www.nationalmssociety.org/Brochures-Vitamins.asp

Brochures

Vitamins, Minerals, and Herbs in MS
An Introduction
by Allen Bowling, MD, PhD
and Thomas Stewart, JD, PA-C

INTRODUCTION

This booklet focuses on the use of popular vitamins, minerals, and herbs by people with multiple sclerosis (MS). The use of these supplements is one form of complementary and alternative medicine, which we’ll call CAM.

CAM is difficult to define, in part because its contours continually shift. One definition describes CAM as therapies that are not commonly taught at U.S. medical schools nor commonly available at U.S. hospitals. Almost by definition, then, this booklet explores controversial and incompletely studied treatments.

Accordingly, this booklet is not intended to be a primary source for understanding the standard, evidence-based, treatment of multiple sclerosis. Rather, it is intended for those who already use, or at least understand, the benefits of mainstream medical interventions. Over the last decade, medications have been developed that modify or slow down MS. The majority of people with MS should be using one of these medications under the supervision of a physician with expertise in treating MS.

Despite these medications, MS remains a chronic disease that is sometimes relatively benign, but sometimes frighteningly unpredictable. For this and other reasons, many people with MS use some forms of CAM therapy. Most, but not all of them, use CAM therapies in addition to, rather than instead of, medical treatments. That means that CAM therapies are usually used in a complementary, rather than an alternative, manner. Taking dietary supplements is one of the most popular CAM treatments.

Most treatments, including the ones listed in this booklet, have risks associated with them. This booklet will identify some of the risks associated with selected vitamins, minerals, and herbal supplements in MS. However, because of a lack of well-conducted scientific studies and the enormous variation in individual clinical situations, not all risks can be identified. Readers should always discuss their personal situation with their physician before using any CAM therapy.

In “General Information for Evaluating Supplements” below, we provide some basic information that relates to supplements generally, and, in “Specific Information about Select Vitamins, Minerals, and Herbs” below, we offer more detailed information relating to some of the most commonly used vitamins, herbs, and minerals.

For additional information on supplements and other forms of CAM, see the section on references below. The information presented here was developed through the Complementary and Alternative Medicine Program of the Rocky Mountain MS Center, in Englewood, Colorado.

GENERAL INFORMATION FOR
EVALUATING SUPPLEMENTS

To weigh the pros and cons of dietary supplements fairly requires a basic understanding of the role of the immune system in MS. Thoughtful supplementation also requires an understanding of evidence about safety and effectiveness, dosing issues, and the law relating to supplements.

In MS, the immune system actively damages myelin, the protective covering of nerves in the brain and spinal cord—the central nervous system. Most treatments for MS involve the attempt to down-regulate the immune system. All supplements should be considered in light of their potential effects on the immune system.

The details of the immune system are very complex, but in general it may be best to assume that in MS, immune stimulation may be dangerous and immune down-regulation may be beneficial. Accordingly, supplements that are supposed to “boost” or “improve” immune function may be the worst choice for people with MS.

Unfortunately, the immune effects of many supplements are poorly understood. Often the use of supplements requires users to make reasonable inferences based on limited evidence. However, inferences may seem reasonable and still be mistaken.

Often what is used to support the use of supplements is simply a story, sometimes called “anecdotal evidence”. This is the least reliable of all the various kinds of evidence. Particularly in MS, where symptoms come and go unpredictably, improvement in symptoms may appear to be related to the use of supplements, when it is not.

The best evidence is generally obtained from carefully controlled trials among a large group of people with MS. Another source of evidence is animal studies. These studies can be helpful, but may also be misleading. Evidence can also be obtained from experiments done in laboratories. Again, these studies are helpful, but can’t be considered definitive in any way.

Dose is always a critical factor in any medication, and more is not always better. Supplements may have different effects depending on the size of the dose that is taken. While a small amount of certain supplements may be useful, larger amounts may be dangerous. Proper dose should always be considered before beginning supplementation. And therein lies a current difficulty.

The Dietary Supplement Health and Education Act of 1994 (DSHEA) has important implications for users of supplements. Unlike some other countries, the U.S. federal government does not regulate supplements as it does drugs. Under DSHEA, sellers of supplements are not required to meet rigorous quality standards or to prove the effectiveness of their products. This means it is not easy to be certain of the amount of active ingredient in many herbal supplements. Users of any supplements should exercise caution regarding marketing information from the seller.

SPECIFIC INFORMATION ABOUT SELECT
VITAMINS, MINERALS, AND HERBS

The number of available vitamins, minerals, and herbs is too great to catalogue here. This booklet reviews only a few vitamins, minerals, and herbs that are most popular with people with MS.

Vitamins
Vitamins are chemicals without caloric content that are necessary for health. With the exception of vitamin D, we must obtain them from dietary sources.

The Food and Nutrition Board of the National Academy of Sciences has established a recommended daily allowance (RDA) or adequate intake (AI) for vitamins. In general, the RDA used in this text refers to the guidelines established for those who are 19-50 years old, without considering other factors, such as breast-feeding and pregnancy. The RDA or AI represents the minimum amount for each vitamin that we should obtain from our diet on a daily basis. On that point, there is little disagreement.

On the other hand, the question of whether larger doses of vitamins are beneficial is controversial. Vitamins do not function in isolation from one another, but rather work in careful balance. Accordingly, a high concentration of one vitamin might cause a relative deficiency of another.

Dietary sources of vitamins, such as fruits and vegetables, appear to be preferable to vitamin supplements. Perhaps this is because fruits and vegetables contain vitamins in useful proportions, as well as fiber, minerals, and other unidentified chemicals found in plants that together play a role in good nutrition and disease prevention.

Vitamins that are of particular relevance to people with MS are vitamin D, the antioxidant vitamins, and vitamin B12. A description of each follows.

Vitamin D
Vitamin D is a hormone, or chemical messenger, in the body. Dietary sources of vitamin D include fish and fortified foods, such as dairy products and breakfast cereals.
Vitamin D is produced in the skin in response to sunlight, but this production is limited by geographic location, skin pigmentation, and season. Some researchers have studied populations and suggested that there is a correlation between low vitamin D levels and MS.

Scientific studies indicate that vitamin D alters immune function in a way that may be desirable in MS. In addition, a handful of studies using an animal model of MS provide further support for the idea that vitamin D plays a protective role in MS.

One recent, large-scale study involving nurses suggested that those who had highter vitamin D intakes, in the form of multivitamin supplements, may have had a reduced risk of developing MS. However, this study did not determine whether vitamin D can have a positive impact on the course or severity of MS in people who already have the disease. Further research is necessary to clarify these findings.

A much better understood role for vitamin D among people with MS relates to its part in maintaining bone density. There is increasing awareness that low bone density (osteoporosis) may be under-diagnosed in many people, including those with MS. Importantly, many people with MS have risk factors for developing osteoporosis:

  • female gender

  • decreased physical activity

  • decreased exposure to sunlight

  • frequent treatment with steroids

People with MS who have these risk factors may wish to consider having bone density tests and taking supplements of vitamin D and calcium (see page 19). Recommended intake of vitamin D is 200 to 600 IU daily. Doses greater than 2,000 IU daily may cause toxic effects, and should not be used unless prescribed by a physician.

 

 

The Antioxidant Vitamins
A free radical, also called an oxidant, is a molecule that contains an unpaired electron. The unpaired electron is highly unstable and generally allows the molecule to react with other nearby substances. The antioxidant vitamins include vitamin A (or its safer form, beta-carotene), vitamin C, and vitamin E. As the name implies, antioxidants tend to decrease the damage caused by oxidants or free radicals. Antioxidant vitamins are generally available in fruits and vegetables.

Preliminary evidence suggests that the damage caused by free radicals may be involved in the disease process in MS. A few studies using an animal model of MS suggest that antioxidants may even be therapeutic. But the value of these animal studies is limited. There are no well-documented published studies of people with MS that show a clinical benefit related to antioxidant supplements.

The safety of taking antioxidants for people with MS has not been established either. One small, five-week study indicates that antioxidants are safe for people with MS, but the study is too small and short to be conclusive.

There is an important theoretical risk to consider. Antioxidant vitamins stimulate the immune system in laboratory experiments and in some groups of people. In MS, where an overactive immune system appears to be part of the disease process, stimulation may be dangerous.

In summary, there is limited evidence suggesting that antioxidants may be beneficial, and there is also some evidence suggesting potential harm.

The most reasonable course may be for people to obtain antioxidants by eating 2-4 servings of fruits and 3-4 servings of vegetables every day. If antioxidant supplements are used, it may be best to use them in moderation.

 

 

 

 

Specific Issues Regarding the Antioxidant Vitamins

  • Vitamin A and Pregnancy—Vitamin A is necessary for vision and promotes normal growth and differentiation of cells in the body. Vitamin A is fat soluble, and is found in liver, eggs, and cod liver oil.

Fat soluble vitamins are stored in the body and high levels may accumulate over time. The RDA for women and men is 2,300 and 3,000 IU per day, respectively. In general, people should avoid doses in excess of 10,000 IU per day. Some studies have concluded that vitamin A in amounts greater than 10,000 IU may produce birth defects. Pregnant women taking cod liver oil (which contains vitamin A) must use caution to ensure that they are not consuming excessive amounts. In general, pregnant women should obtain vitamin A in the form of beta-carotene found in fruits and vegetables.

  • Vitamin C and Urinary Tract Infections—Vitamin C, also known as ascorbic acid, plays a role in building and maintaining body tissues. Vitamin C is readily available in foods such as citrus fruits and tomatoes. The RDA for this vitamin is 90 milligrams for men and 75 milligrams for women under normal circumstances. The RDA for smokers is an additional 35 milligrams.

For a variety of reasons, people with MS tend to be at an increased risk for urinary tract infections. Some people supplement with vitamin C to reduce that risk. The theory in support of that practice is that vitamin C supplementation can acidify the urine, thereby creating a challenge to infection-causing bacteria. However, the weight of evidence suggests that vitamin C does not acidify urine. There is more evidence to support the use of cranberry (see below) to prevent urinary tract infections than there is for vitamin C.

Whether a higher intake of vitamin C is beneficial is controversial. The proper dose of vitamin C (and all other vitamins) for people with MS is unresolved. Some authorities believe that daily doses greater than 1,000 milligrams may cause diarrhea or kidney damage.

  • Vitamin E and Polyunsaturated Fatty Acids (PUFAs)—Vitamin E prevents oxidative damage to cell membranes or linings and can be obtained from vegetable oils, fruits, vegetables, nuts, and meat. The RDA for vitamin E is 22.5 IU for both men and women.

The body’s requirements for vitamin E increase as the intake of polyunsaturated fats (PUFAs) in the diet increases. This is relevant to MS because some people increase their consumption of PUFAs in the hope that PUFAs are beneficial in MS.

In general, the additional amount of vitamin E needed in diets that are high in PUFAs is quite low: approximately 0.6 to 0.9 additional IU of vitamin E is needed for each additional gram of PUFA. This means that a person consuming 25-30 grams of PUFAs daily needs 15-27 IU of vitamin E daily.

Daily vitamin E doses greater than 1000 IU should be avoided. Consuming substantially lower doses of vitamin E (in the range of 100 IU or less) may be preferable in light of the unresolved questions about the immune effects of vitamin E in people with MS.

 

 

Vitamin B12
Vitamin B12 is found in eggs, meat, poultry, shellfish, and dairy products. The RDA for vitamin B12 is 2.4 micrograms/day for both men and women. Also known as cobalamin, vitamin B12 is required for the production of red blood cells and for proper function of the nervous system.
In fact, a severe vitamin B12 deficiency produces neurological symptoms similar to those seen in people with MS.

A variety of observations have suggested that there may be a relationship between B12 levels and MS. For example, people with MS have low levels of vitamin B12 in their blood more frequently than the general population. Some have unusually large red blood cells. This can sometimes be caused by low vitamin B12.

For all people with MS to supplement with vitamin B12 on the basis of these associations would be a mistake. However, B12 deficiency can be evaluated through a blood test. People with low levels should consider vitamin B12 supplementation. For other people with MS, there is no evidence that vitamin B12 either improves neurological symptoms or favorably alters the course of the disease.

Minerals
Minerals are elements widely distributed in nature that perform diverse and critical roles in human health and disease. The potential roles of selenium, calcium, and zinc are considered here.

S
e

Selenium
Selenium is a mineral that has antioxidant effects. For a brief review of the relevance of antioxidants in MS, see the section on antioxidant vitamins on page 12. As with the other antioxidants, it is difficult to determine the exact effect that selenium has on people with MS. Good sources of selenium include seafood, legumes, whole grains, low-fat meats, and dairy products.

Some studies indicate that selenium levels may be lower in people with MS than in the general population. Partly based on that observation, some have speculated that increased amounts of selenium might have beneficial effects in people with MS.

However, in a study using laboratory animals, selenium supplementation worsened an MS-like disease. In one five-week human study, selenium supplementation seemed to be safe. However, that study was too short and involved too few people to reliably assure safety. Furthermore, selenium may increase the immune response, which may be undesirable in people who have MS.

For adults over the age of 19 the RDA of selenium is 55 micrograms. Until more information is available, it may be best for people with MS to obtain selenium from foods or to use selenium supplements only in moderation. Toxic effects may occur with daily doses greater than 200 micrograms.

 

C
a

Calcium
Important in the formation of teeth and bone and in the regulation of many body processes, calcium is the most abundant mineral in the human body. Good food sources for calcium include dairy products, eggs, and green leafy vegetables.

An old hypothesis about the cause of MS connected it to calcium intake. Based on the studies of populations, the incidence of MS appeared linked to high intake of milk during childhood followed by a large or sudden reduction in milk drinking during adolescence. Very little evidence supports this hypothesis.

On the other hand, calcium is a critically important supplement for those who are at risk for very thin bones, or osteoporosis. As indicated in the section on vitamin D above, many people with MS have risk factors for osteoporosis.

People between the ages of 19 and 50 should consume 1,000 mg of calcium in the diet. Daily doses greater than 2,500 milligrams should be avoided.

 

Z
n

Zinc
Zinc is a mineral that plays a role in many different processes in the body. The results of limited studies of MS and zinc are unclear.
Some studies indicate that zinc levels are low in people with MS. Other studies indicate that zinc levels are high in MS, that zinc may activate the immune system, and that zinc supplementation may worsen an animal model of MS.

The RDA for zinc is 11 mg for men and 8 mg for women. Given the uncertainties about zinc and MS, it would seem preferable for people with MS to avoid doses of zinc in excess of the RDA.

Herbs
The word herb generally refers to a plant, or part of a plant, used for medicinal purposes. Herbs, like drugs, interact with the cells of the body and can sometimes produce changes in body processes. The changes produced by both herbs and drugs may be beneficial, but they may also be harmful.

To minimize the risk of harmful side effects, herbs should only be used with caution. Herb users should be aware of proper dosing, potential side effects, and potential drug-herb and herb-herb interactions. It is important to recognize that there are many unknown aspects to herbs. Specifically, herbs contain many different chemicals. Their effects on the body, on different diseases (such as MS), and on drugs have not been fully determined. In addition, the quality and composition of herbal preparations currently marketed in the United States are extremely variable.

The six herbs described below are among those commonly considered to have potential relevance to people with MS.

Ginkgo Biloba
Ginkgo comes from one of the oldest tree species and has been used in China for medicinal purposes for thousands of years. There is some limited evidence to support ginkgo’s ability to improve cognitive function among older people with mild to moderate dementia. There is no evidence that it improves memory or concentration in healthy adults or people with MS.

Ginkgo is an antioxidant (the function of antioxidants is discussed above). It also inhibits a substance known as platelet activating factor (PAF). By inhibiting PAF, ginkgo can cause a decrease in the activity of certain immune cells. These activities provide theoretical support for the use of ginkgo to treat MS.

Ginkgo has been studied in both the animal model of MS and in people with MS. In the animal model, ginkgo decreased disease activity. Two studies have been done in people. One suggested a benefit, but the larger of the two trials suggested no benefit. In that study, ginkgo was used to treat exacerbations, or attacks, of MS. The study did not consider whether ginkgo might have a role in preventing attacks or in improving MS-related cognitive dysfunction.

Few serious side effects with ginkgo supplementation are known. Ginkgo may inhibit blood clotting and therefore should be avoided by people with bleeding disorders, those who take blood-thinning medications, and those who plan elective surgery. In all cases, regular ginkgo use should be reported to all health-care providers.

 

 

Echinacea
Echinacea, an extremely popular herb, is a flowering plant native to North America and a member of the daisy (Asteraceae) family.
Of the three species available, the best studied is echinacea purpurea.

Echinacea is generally used to treat the common cold. Some studies suggest that it may be helpful for decreasing the duration and symptoms of the common cold. But many studies of echinacea have been criticized by scientists for being poorly designed and performed. No definitive conclusion can be drawn regarding the efficacy of echinacea to treat colds.

Because viral respiratory infections may be linked to exacerbations or acute attacks of MS, treating colds with echinacea is an appealing strategy. The problem is that echinacea may stimulate the immune system. This is a theoretical risk for people with MS because their immune systems are already inappropriately stimulated. No study has been done to investigate this theoretical risk in people with MS.

 

 

St. John’s Wort
St. John’s wort is a yellow flower that grows in many parts of the world. It is generally used as an antidepressant. Many studies indicate that St. John’s wort indeed has antidepressant effects. However, the claim was not supported by data from the first large-scale multicenter clinical trial of St. John’s wort versus an inert placebo or Zoloft. This trial, conducted by the National Institute of Mental Health, National Center for Complementary and Alternative Medicine, and the federal Office of Dietary Supplements, was completed in 2002. It concluded that St. John’s wort is not effective in treating major depression of moderate severity. The NIMH and cosponsors are now planning to study the herb in people with mild depression.

St. John’s wort is generally well tolerated and no reported study has identified effects on the immune system that could be concerning to people with MS.

Interaction with other medications is one important risk of using this herb. St. John’s wort appears to alter the body’s metabolism of certain drugs, which may include birth control pills and drugs commonly used to treat heart disease, seizures, certain cancers, and depression. Medications taken by people with MS that could possibly be affected by St. John’s wort include amitriptyline (Elavil), nortriptyline (Pamelor), carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin) and primidone (Mysoline).

There is a relatively high incidence of depression among people with MS. It is important to recognize that depression should not be self-diagnosed or self-treated. If you think that you may be a candidate for treatment with St. John’s wort, you should first seek a professional evaluation. St. John’s wort is not suitable for anyone with severe depression.

 

 

Valerian
The unpleasant-smelling root of a flower called valerian is sometimes used as a sleep aid. (It is also sometimes used in root beer!) People with MS may have difficulty sleeping, and difficulties with sleep may contribute to MS-related fatigue. Thus, a sleep aid may be very useful to some people with MS.

A few well-designed trials not involving people with MS show that valerian can decrease the amount of time required to fall asleep without residual feelings in the morning. Valerian is usually well tolerated. However, its immune effects have not been studied.

People with fatigue should consider the possibility that their fatigue may worsen when they take valerian as it may have a lingering sedating effect. Also, valerian may increase the sedating effects of prescription medications such as diazepam (Valium), baclofen (Lioresal), and tizanidine (Zanaflex).

 

 

Asian Ginseng
Asian ginseng, also known as Panax ginseng, has been used for centuries by the Chinese for its supposed ability to enhance physical performance and resistance to stress and aging. The evidence in support of these vague claims is not very strong. One clinical study supported the use of ginseng to enhance quality of life, and another study showed an improvement in the speed of mathematical computations among college students. But other studies have failed to find benefits.

An herb that increases energy and strength would be of great use to people with MS who sometimes suffer from debilitating fatigue. Although some evidence suggests ginseng might be safe in people with MS, other experiments raise the possibility that ginseng may stimulate the immune system in ways that may be detrimental to people with MS. In short, there is too little evidence to conclude whether ginseng is safe for people with MS or not, and nothing to indicate that it improves energy or strength.

 

 

Cranberry
Cranberry is grown in bogs in North America for juice, jelly, and seasonal decorations. Many people use the ripe fruit from this plant to prevent or treat urinary tract infections.

Evidence suggests that cranberries prevent bacteria from sticking to the cells that line the urinary tract. This unique action of cranberry is attributed to two compounds, fructose (a type of sugar), and another chemical known as proanthrocyanidin. Recently published preliminary evidence suggests that cranberry may also kill bacteria directly.

Cranberry has very few side effects. Therefore, using cranberry tablets or juice to prevent urinary tract infections is probably reasonable. Increased fluid intake and improved hygiene may also be helpful preventive measures.

Cranberries should never be used to treat existing urinary tract infections. Urinary tract infections can have serious consequences for people with MS. Urinary tract infections require immediate antibiotic treatment from a physician to get them under control quickly.


CONCLUSION

People with MS and other chronic diseases often consider using complementary and alternative medicine (CAM). Doing all that one can to live well with MS is reasonable, but the use of CAM implies that people accept important responsibilities as well.

Nowhere in this booklet do we recommend any particular treatment. Rather, the pros and cons for each are described as well as space and available data permit. As with most CAM treatments, the evidence regarding dietary supplements is inconclusive. The lack of better evidence is frustrating. Nevertheless, an inquiry into CAM can also be rewarding.
It may help restore a sense of control and hope to people who are struggling with an unpredictable disease. Hope and a good quality of life are tightly linked, and both should be cultivated.

We hope this booklet provides enough useful and specific information to allow more informed decision-making about the supplements we described. Just as importantly, we hope that it provides a framework for thoughtful consideration of other CAM treatments not discussed here.

REFERENCES

Web sites

  • The National MS Society offers local referrals, education programs, counseling, self-help groups, and other booklets and brochures on MS.

  • Regularly updated information focused on CAM and MS is available on an interactive Web site at www.ms-cam.org. This site is managed by the Rocky Mountain MS Center.

Non-technical books
There are many non-technical books on CAM. One book that specifically deals with CAM and MS is:

  • Bowling A.C. Alternative Medicine and Multiple Sclerosis. New York: Demos Medical Publishing, 2001. Web site: www.demosmedpub.com. Tel: 800-532-8663.

Other non-technical books with objective general information on dietary supplements and CAM are:

  • Dillard J., Ziporyn T. Alternative Medicine for Dummies. Foster City, CA: IDG Books Worldwide, Inc., 1998.

  • Steven Foster and Varro E. Tyler, PhD, Tyler’s Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. Binghamton, NY: Haworth Press. Web site: www.haworthpressinc.com. Tel: 800-HAWORTH.

Note: The above-mentioned books may be available for loan at your local chapter of the National MS Society, or at your public library.

Technical References
Detailed technical references include:

  • 2004 Physicians’ Desk Reference for Nonprescription Drugs and Dietary Supplements, Thomson Healthcare, NJ. Web site: www.pdrbookstore.com; Tel: 800-232-7379.

  • Physicians’ Desk Reference for Herbal Medicines, Second Edition, Thomson Healthcare, NJ. Web site: www.pdrbookstore.com; Tel: 800-232-7379.

  • Bowling, A., Stewart, T. Current complementary and alternative therapies for multiple sclerosis. Current Treatment Options in Neurology, 5:55-68, 2003.

  • Ernst, E., Pittler, M.H., Stevinson, C., White, A. The Desktop Guide to Complementary and Alternative Medicine: An Evidence-Based Approach. London: Mosby, 2001.

  • Fetrow, C., Avila, J. The Professional’s Handbook of Complementary and Alternative Medicines. Springhouse, PA: Springhouse Corp., 2003.

  • Fragakis, A.S. The Health Professional’s Guide to Popular Dietary Supplements. Chicago, IL: The American Dietetic Association, 2003.

  • Jellin J.M., Batz F., Hitchens K., et al. Natural Medicines Comprehensive Database. Stockton, CA: Therapeutic Research Faculty, 2002.

Sources of information on health fraud

  • National Council Against Health Fraud, 119 Foster Street, Peabody, MA 01960. Tel: 978-532-9383. Web site: ncahf.org.

  • Quackwatch. Web site: www.quackwatch.com.

Federal government sources

  • Federal Trade Commission, Consumer Response Center, 600 Pennsylvania Avenue, NW, Washington, DC 20580. Tel: 877-FTC-HELP (877-382-4357). Web site: www.ftc.gov. Investigates false advertising.

  • Food and Drug Administration, 5600 Fishers Lane, Rockville, MD 20857. Tel: 888-463-6332. Web site: www.fda.gov. In 1988, the FDA established the National Health Fraud Unit to fight medical fraud. This unit helps coordinate federal, state, and local regulatory actions against fraudulent products and practices.

  • National Center for Complementary and Alternative Medicine Clearinghouse, P.O. Box 7923, Gaithersburg, MD 20898-7923. Tel: 888-644-6226. TTY: 866-464-3615. Web site: nccam.nih.gov. E-mail: info@nccam.nih.gov.

  • U.S. Postal Inspection Service, 475 L’Enfant Plaza, SW, Washington, DC 20260-2100. Tel: 202-268-4267. Web site: www.usps.gov/postalinspectors. Monitors products purchased by mail.

 

 

 

 

For additional information

Putting the Brakes on MS (Society brochure)

Complementary and Alternative Medicine

Managing MS Through Rehabilitation (Society brochure)

 

 

 

Allen Bowling, MD, PhD, is the Director of the Complementary and Alternative Medicine Program at the Rocky Mountain MS Center, and Clinical Assistant Professor of Neurology at the University of Colorado Health Sciences Center.

Thomas Stewart, JD, PA-C, is a certified physician assistant and is the Associate Director of the Complementary and Alternative Medicine Program at the Rocky Mountain MS Center.

Cover photograph by Bill Stanton.

This publication is supported by contributions to the National Multiple Sclerosis Society from its members and friends.

Reviewed by members of the Client Education Committee of the National Multiple Sclerosis Society’s Medical Advisory Board.

 

 

 

Copyright © 2004 National Multiple Sclerosis Society

 

8.4. Defesas Celulares e a vitamina do Sol. Scientific American, edição 67 – Dezembro 2007. Cientistas reconhecem que a vitamina D faz mais que contribuir para o fortalecimento dos ossos. Mas a maioria das pessoas não a obtém em quantidades satisfatórias. Essa deficiência estaria contribuindo para o avanço de doenças mais graves.

http://www2.uol.com.br/sciam/reportagens/defesas_celulares_e_a_vitamina_do_sol.html

8.5. Mistérios do Cérebro – A relação com os alimentos. http://globoreporter.globo.com/Globoreporter/0,19125,VGC0-2703-14904-3,00.html
Fim de um mito
Globo Repórter em 2006 – Foi falado sobre os beneficios do ovo, gema crua e clara cozida. A gema do ovo tem colina. Consumir mais fFrutas, verduras e ovo.

 

8.6. A neurogenese é inibida pelo processo emocional depressivo.

Adult neurogenesis is the production of new neurons in areas of the adult brain including the subventricular zone (SVZ) and subgranular zone (SGZ) of the hippocampus [28]. This formation of new neurons plays a number of physiological roles including damaged neuron replacement[29], [30], memory formation [31], [32] and response to stress [33]. Moreover, some reports have recently shown that neurogenesis is involved in depression [34], [35]. disponível em

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2270335

8.7. As 5 FORMAS DE PROTEGER SEU CÉREBRO.
Dr. Cicero Galli Coimbra, M.D., Ph.D. Laboratory for Brain Ischemia Research, Head Department of Neurology and Neurosurgery Federal University of São Paulo. Escola Paulista de Medcina.

Viva Saúde

http://revistavivasaude.uol.com.br/edicoes/23/artigo15542-1.asp

“Manter a saúde mental é mais fácil do que muita gente imagina. As pesquisas dos últimos 10 anos apontam ser possível, sim, estimular a formação de novos neurônios (o que até 1998 a ciência considerava impossível!) e, conseqüentemente, afastar os riscos de doenças como Parkinson e mal de Alzheimer.”

8.8. Estimulando a natureza do ser humano com ambiente e alimentação natural, equilibrando e suprindo as deficiências de nutrientes, suplementos e vitaminas, os neurônios podem regenerar o corpo. Na dec. de 2000 os cientistas da neurologia descobriram que o processo de degeneração é desencadeado por abalo e estresse emocional. Daí verificaram que existe no sangue deficiência de nutrientes.

Jornal da Paulista

Estudo revela que portadores da doença apresentam deficiência da vitamina.

http://www.unifesp.br/comunicacao/jpta/ed179/pesquisa4.htm

Estudo comprova que carne vermelha prejudica pacientes com Mal de Parkinson – vídeo Globo

http://video.globo.com/Videos/Player/Noticias/0,,GIM839564-7823-ESTUDO+COMPROVA+QUE+CARNE+VERMELHA+PREJUDICA+PACIENTES+COM+MAL+DE+PARKINSON,00.html

 

O remédio da serenidade

Quinta-Feira , 19 de Junho de 2008

 

http://jornalhoje.globo.com/JHoje/0,19125,VJS0-3076-20080619-324034,00.html

A evolução da doença degenerativa sem os cuidados necessários pode fazer uma realidade assustadora em poucos anos de vida.

 

From: Robert Rodgers, Ph.D.

robert@parkinsonsrecovery.com

Sent: Thursday, July 10, 2008 11:46 AM

Subject: Natural versus Artificial Remedies

Parkinsons Recovery


The Difference Between a Natural and Artificial Treatment


People we work with are often perplexed by what constitutes a “natural therapy” for Parkinson’s. The fundamental question is this:

“How do I know the difference between a ‘natural treatment’  and an ‘artificial treatment”?

That is to say, how do I know whether or not what I am currently doing to treat my Parkinson’s is what my body needs and wants? As it turns out the answer is deceptively simple:  Your body knows what it needs.

John Coleman ND, MANPA, MBTAV.

Mudança do estilo de vida é necessaria. As informações provam isso. Os dados são científicos e médicos, e estes trabalhos estão
à livre disposição de qualquer leitor da internet.

Estas informações, especificamente sobre alimentação natural associada aos  suplementos (e excluir fumo, bebida alcoólica, frituras, artificiais, gordura animal, doçuras, alimentos cozidos em altas temperaturas – quanto mais cru, mais saudável e preserva as vitaminas do alimento) combinados com o fim da tristeza e estresse emocional, mudança do estilo de vida e das escolhas pessoais, correspondem à única maneira de evitar a neurodegeneração.

A ciência e a medicina sabem que o corpo humano cria todos os dias neurônios e células-tronco. É verdade, acontece a neurogênese. A neurogenese permite a juventude e regeneração sonhadas. De um modo muito natural, a preservação do corpo humano e do cérebro acontecem.

  1. 9.    A necessidade de cuidados especiais.

 

Indisposições, doenças do Sistema Nervoso Central exigem a permanência de CUIDADOS ESPECIAIS apropriados para cada quadro de diagnóstico e sintomatologia, para a conservação da vida e saúde das pessoas, manutenção e melhora da qualidade de vida das mesmas.Na esclerose múltipla, HÁ TERAPIAS INDISPENSÁVEIS para serem efetivadas permanentemente. Tal tratamento começa pela AÇÃO PREVENTIVA.

 

 

São Jose, 1º de setembro de

2008.

Cristiane Rozicki

35 Respostas

  1. […] CETRA hires VideoNet to Help with MS Biking EventA Cura e prevenção ocorrem por terapia natural. Suplementação de vitaminas, dieta alimentar […]

    Testimonials and Press Releases

    Welcome to DIRECT-MS.org
    http://www.direct-ms.org/

    Testimonials
    Anytime a person is contemplating using a new therapy, they are most interested in hearing about what other people have experienced with that therapy. Such information carries no weight in the world of science, and rightly so. However, if a therapy has value, then one can expect there will be numerous accounts of success.

    Below are anecdotal accounts from people who have used nutritional strategies to control MS. The most famous account is that of Roger McDougall, a British screenwriter who regained his health and achieved a permanent remission though the use of dietary changes. He did this in the 1950s, and remarkably, many of his strategies are those that are now recommended on the basis of scientific data collected after 1960.

    Roger McDougall Story
    No Bed of Roses, by Roger McDougall
    http://www.direct-ms.org/testimonials.html

  2. […] A Cura e prevenção ocorrem por terapia natural. Suplementação de vitaminas, dieta alimentar […]

    Dietary micronutrients/antioxidants and their relationship with bronchial asthma severity

    1. C. Picado1,
    2. R. Deulofeu2,
    3. R. Lleonart3,
    4. M. Agustí3,
    5. J. Mullol3,
    6. M. Torra4,
    7. L. Quintó4

    Article first published online: 23 SEP 2008

    DOI: 10.1034/j.1398-9995.2001.00793.x

    Issue

    Allergy

    Volume 56, Issue 1, pages 43–49, January 2001

    http://onlinelibrary.wiley.com/doi/10.1034/j.1398-9995.2001.00793.x/full

    Keywords:

    · antioxidants;
    · bronchial asthma;
    · diet;
    · micronutrients

    Abstract

    1. Top of page
    2. Abstract
    3. Material and methods
    4. Results
    5. Discussion
    6. Acknowledgments
    7. References
    Background: Because little is known about micronutrient/antioxidant intake and asthma severity, we investigated dietary intake and plasma/serum levels of micronutrients/antioxidants in a group of asthma patients with various degrees of severity, and compared the results with healthy subjects.

    Methods: A case control study was carried out on 118 asthma patients and 121 healthy subjects. The severity of the disease was classified by division of patients into four groups. Normal dietary micronutrient/antioxidant intake was estimated from a food frequency questionnaire. Plasma/serum levels of vitamins C, E, and A, selenium, magnesium, zinc, and platelet glutathione peroxidase (GSH-Px) activity were also determined.

    Results: No differences in daily micronutrient/antioxidant intake were seen between patients and healthy subjects. The severity of the disease showed no significant relationship with micronutrient/antioxidant intake. There were no differences in plasma/serum levels in any of the micronutrients/antioxidants between healthy subjects and asthmatics. Nor were any differences found between asthma groups in severity in the biochemical measures, except in platelet GSH-Px activity, which was significantly lower in the most severe groups.

    Conclusions: In this study, we found no evidence of any association between micronutrient/antioxidant intake or plasma/serum levels of micronutrients/antioxidants and asthma. Reduction of platelet GSH-Px activity in the most severe patients suggests that these patients have a diminished capacity to restore part of the antioxidant defences.

    Recent studies suggest that an association may exist between a low intake of certain micronutrients and asthma (1). It has also been hypothesized that a deficient antioxidant capacity may also play a role in the patho-genesis of asthma (2).

    Human antioxidant defences include ascorbic acid (vitamin C), α-tocopherol (vitamin E), vitamin A, enzymes such as glutathione peroxidase, and trace elements including selenium and zinc.

    Low intake of vitamin C has been associated with wheezing (3, 4), increased risk of bronchial hyperresponsiveness (5), and reduced levels of FEV1 (6, 7). Dietary intake of vitamin E has a positive influence on wheezing (8) and lung function (8). Low dietary intake of vitamin A has been shown to be associated with airflow limitation (9).

    Selenium is an essential component of glutathione peroxidase (GSH-Px). It has been suggested that lowered GSH-Px activity due to a low intake of selenium may play a role in asthma (10–13).

    Many studies have evaluated the effect of the dietary intake of micronutrients and antioxidants on wheeze (3, 4, 8), lung function (6–9), and bronchial hyperreactivity (5), as assessed by challenge tests. However, neither the presence of wheeze, the demonstration of bronchial hyperresponsiveness, nor low lung function can be used as a substitute for the diagnosis of asthma.

    In epidemiologic studies the potential impact of both the severity of the disease and its treatment on the characteristics of asthma patients’ diet should also be considered. One example of the possible influence of asthma therapy on the diet is the severe corticosteroid-dependent patient who modifies his/her diet to reduce caloric intake in order to prevent weight gain resulting from the use of systemic corticosteroids. Reduction or modification of dietary intake in these patients can be accompanied by a low intake of micronutrients and antioxidants. Therefore, in order to elucidate the role of dietary factors in asthma, it is important to perform studies on patients with a clearly defined diagnosis of asthma. In addition, only patients with diets not influ-enced by food supplementation or avoidance should be included in the study. In a recent study, we reported that asthma is associated with a decrease in energy intake (14). We also found severe asthma with regular oral corticosteroid therapy to be associated with reduced plasma protein and albumin levels (14).

    Although a number of studies have evaluated the possible role of dietary micronutrients/antioxidants in asthma, little is known about the influence of either the severity of the disease and/or its treatment on intake and on the plasma/serum levels of these micronutrients.

    The objective of our study was to investigate whether a relationship exists between the dietary intake of micronutrients/antioxidants and asthma. We also studied the effects of asthma severity on plasma/serum levels of vitamins, selenium, magnesium, and zinc, and platelet GSH-Px activity.

    Material and methods

    1. Top of page
    2. Abstract
    3. Material and methods
    4. Results
    5. Discussion
    6. Acknowledgments
    7. References

    Study subjects

    A total of 150 consecutive asthmatic patients attending the outpatient clinic were asked to take part in the study. They all presented a history of intermittent wheezing, shortness of breath, and chest tightness; they all had a diagnosis of asthma and were taking asthma medication. The severity of the disease was characterized in four groups of patients by a method similar to the one proposed in the Global Initiative for Asthma (GINA) (15). This method was modified in order to include the characteristics of therapy in the classification of the severity of disease. The four groups were as follows: intermittent (group 1), mild persistent (group 2), moderate persistent (group 3), and severe (group 4). Group 1 comprised patients who were on β2-adrenergic agents on demand. Group 2 comprised patients who regularly used β2-adrenergic agents, with or without low doses of inhaled corticosteroids. Group 3 comprised patients with a continuing history of episodic asthma, most of whom were on regular inhaled corticosteroid therapy, and group 4 comprised patients with a current history of chronic unremitting asthma requiring high doses of inhaled corticosteroids and regular oral corticosteroid therapy, or frequent short courses of oral corticosteroids.

    Aspirin-intolerant asthma was deduced from the patient’s history. In patients with only one attack precipitated by aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin intolerance was confirmed by an oral challenge test with aspirin. In patients with two or more asthma attacks precipitated by aspirin or NSAIDs, the oral test was not carried out.

    A total of 150 healthy volunteers were selected as a control population from various sources, including neighbors of patients (n=112), relatives of the staff members (n=10), and the blood donor population (n=28). The control subjects had never had any episode of breathlessness and/or wheezing and had never used asthma medication.

    All subjects lived in the area surrounding the hospital with a very homogeneous middle-class population.

    Only subjects (patients and healthy volunteers) from the native population were included in the study. Smokers, subjects receiving vitamin supplements, or those who were on an exclusion diet were excluded.

    A total of 118 patients and 121 subjects met all the inclusion criteria and agreed to participate in the study. The subjects gave informed consent to the study, which was approved by the ethics committee of the institution.

    The skin prick test was performed with common allergens (Dermatophagoides pteronyssinus, D. farinae, cat, dog, grass-pollen mixture, tree-pollen mixture, Parietaria judaica, Aspergillus fumigatus, Alternaria tenuis, and cockroach) (Ifidesa-Arístegui, Bilbao, Spain). Histamine (10 mg/ml) and glycerol were used as positive and negative controls. A skin prick reaction was regarded as positive if the wheal size was over 3 mm. Subjects were considered to be atopic if they had a positive reaction to any of the allergens in the testing panel.

    Food frequency questionnaire

    All subjects completed a food frequency questionnaire (FFQ). We used a 150-item semiquantitative FFQ to assess usual dietary intake over the previous 6 months. A trained dietitian who was unaware of the subjects’ characteristics administered the FFQ to all the subjects. Micronutrient/antioxidant intake was computed from the reported frequency of consumption of each specified unit of food or beverage, and from published data on the micronutrient/antioxidant content of the specified portions. To help the subjects to quantify food consumption, the dietitian used photographs of servings with six progressive portions of the reported consumed foods.

    Biochemical measurements

    A fasting 100-ml sample of venous blood was taken between 8 and 9 a.m. Serum α-tocopherol (vitamin E) was measured by high-performance liquid chromatography (HPLC), by the method of Shearer (16). Serum retinol (vitamin A) was measured by HPLC by the method of Catigiani & Bieri (17). Whole-blood total ascorbic acid (vitamin C), which includes ascorbic and dehydroascorbic acid, was measured by HPLC by the method of Speek et al. (18). Methods for vitamin measurements were initially calibrated with the standard reference material 968b for fat-soluble vitamins, from the National Institute for Standards and Technology (NIST) (Gaithersburg, MD, USA), and were periodically controlled by participation in the Micronutrients Measurement Quality Assurance Program, also from the NIST.

    Serum selenium concentration was determined by the direct electrothermal atomic absorption spectrophotometric method with palladium as matrix modifier. We used a Perkin-Elmer 3030 spectrometer, HGA-600 fur-nace and AS-60 automatic sampler. The L’vov platform, Zeemand background correction, and other specifications of the STPF (stabilised temperature platform furnace) concept were followed (19). Within-day precision, between-day precision, and the accuracy of the method were confirmed by the analysis of Standard Reference Material SERONORMTR (selenium certified value=86 µg/l).

    Zinc was measured by atomic absorption spectrophotometry.

    Platelet GSH-Px activity was determined by a spectrophotometric assay based on the oxidation of NADPH, by a method previously described in detail elsewhere (20).

    Statistics

    Dietary intake of selenium, vitamin A, vitamin C, and magnesium was skewed; therefore, a logarithmic trans-formation was applied to the data before formal analy-sis. However, summary statistics are reported in the original scale in the text and the tables. Serum vitamin E values were adjusted for total cholesterol (μM vitamin E: mM total cholesterol). Dietary information was analyzed by the method of Willett (21). Correlation between dietary and serum vitamin levels was tested by simple Pearson correlation analyses with crude values. Means of dietary intake and biochemical measurements (adjusted to total energy intake) were compared between patients and controls, and between the four groups of patients, by an ANOVA model adjusting for age and sex. Results were considered statistically significant if the observed two-sided significance level (P value) was not greater than 0.05. Values in the test and tables are means±SEM. Statistical analysis was carried out using SPSSWIN 6.1.3 statistical software (SPSS, Inc., 1989–95).

    We calculated the empirical power of the study, defined as the percentage of significant tests over 1000 samples, by bootstrapping (22).

    Jump to…

    Results

    1. Top of page
    2. Abstract
    3. Material and methods
    4. Results
    5. Discussion
    6. Acknowledgments
    7. References

    Demographic and clinical characteristics

    Demographic characteristics were similar in patients with asthma and control subjects (Table 1). The distrib-ution of patients as regards severity is shown in Table 2. Patients from group 1 were significantly (ANOVA, P<0.01) younger than those with moderate (groups 2 and 3) and severe asthma (group 4).

    Table 1. Demographic data from patients and controls expressed as mean±SEM (range), P value

    Asthma
    Controls
    P

    n 118 121
    Sex (M/F) 48/70 45/76 NS
    Age (years) 41.6±1.4 (16–72) 38.8±1.3 (17–74) NS
    Weight (kg) 65.8±1.2 (40–101) 66.2±1.3 (45–98) NS
    Height (cm) 164.0±0.8 (146–186) 164.8±1.0 (150–188) NS
    Table 2. Demographic data from asthmatic patients according to severity expressed as mean±SEM (range), P value, ANOVA
    Severity
    1
    2
    3
    4
    P

    * Groups 1, 2 vs 4.

    n 30 40 24 24
    Age (years) 29.5±2.2 (16–63) 40.8±2.2 (19–72) 47.2±2.9 (19–67) 50.4±2.3 (44–99) <0.05*
    Weight (kg) 63.0±2.6 (44–99) 64.8±2 (47–101) 65.9±1.7 (48–79) 70.2±3 (40–96) NS
    Height (cm) 165.8±1.6 (150–182) 163.7±1.6 (148–186) 161.7±1.7 (146–180) 165.0±1.9 (148–186) NS
    FEV1 (%) 86.0±1.1 (80–93) 83.0±1.01 (77–91) 74.0±1.2 (62–86) 62.0±2.1 (46–75) <0.05*
    FVC (%) 91.0±1.3 (82–101) 87.0±0.9 (81–95) 84.0±1.2 (75–94) 78.0±1.9 (68–88) <0.05*
    Atopy (%) 67 61 59 39 <0.05*

    In group 1, there were no patients on inhaled corticosteroids. In group 2, 22 out of 40 patients were on inhaled corticosteroids (180±100 mg/day, range 0–400 for 11±19 months). Seventeen out of 24 patients in group 3 were on inhaled corticosteroid therapy (380± 260 mg/day, range 0–800 for 10±15 months), and 19 out of 24 patients in group 4 were on this therapy (1060± 380 mg/day, range 800–2000, for 9±16 months). The mean dose of inhaled corticosteroids was significantly higher (P<0.05) in groups 3 and 4 than in group 2. The difference was also significantly different (P<0.05) between groups 3 and 4. Patients from group 4 had a significantly lower FEV1 (ANOVA, P<0.001) and FVC (ANOVA, P<0.01) than those from groups 1 and 2 (Table 2).

    The prevalence of atopy defined according to the results of the prick test was significantly higher in groups 1 (67%) and 2 (61%) with respect to group 4 (39%) (Table 2).

    Eighteen patients were aspirin-intolerant. They all belonged to groups 3 (14 patients) and 4 (four patients).

    Only patients from group 4 were on regular oral cor-ticosteroid therapy (mean 11.5 mg/day, range 5–20 mg/day) or were receiving frequent short courses of oral steroids.

    Food frequency questionnaire

    The daily micronutrient/antioxidant intakes are given by asthma and control groups in Table 3. No differences in daily micronutrient/antioxidant intake were seen between patients and healthy subjects.

    Table 3. Daily micronutrient/antioxidant intake (crude values) for patients and controls, mean±SEM. ANOVA adjusted for total energy intake, sex, and age

    Patients
    Controls
    P

    Magnesium (mg/day) 330.0±120 363.0±168 NS
    Zinc (mg/day)   10.0±3    11.0±3.3  NS
    Selenium (μg/day)  73.0±20    78.0±35  NS
    Vitamin A (μg/day) 882.0±685 827.0±704 NS
    Vitamin C (mg/day)  159.0±75   165.0±98 NS
    Vitamin E (mg/day)   6.7±2   6.7±2.4   NS

    No differences in micronutrient/antioxidant intake were found between the four groups of asthma patients (Table 4).

    Table 4. Daily micronutrient/antioxidant intake (crude values) for patients according to severity. Mean±SEM. ANOVA adjusted for total energy intake, sex, and age

    Severity

    1
    2
    3
    4
    P

    Patients (n) 30   40 24 24
    Magnesium (mg/dl) 358.0±155  321.0±78 336.0±153 328.0±69 NS
    Selenium (mg/day) 79.0±17   68.0±16 67.0±16 75.5±27 NS
    Zinc (mg/day) 11.3±3.6   9.9±2.4 9.6±2.2 10.3±3.4 NS
    Retinol (vitamin A) (μg/day) 1005.0±981 673.2±419 990.0±581 968.0±658 NS
    Vitamin C (mg/day) 177.0±76   147.0±69.9 162.0±82  152.0±74 NS
    Vitamin E (mg/day) 7.6±1.8    6.4±1.8 6.5±2.0 6.4±2.1 NS

    No differences in the characteristics of micronutrient/antioxidant intake were found between atopic and nonatopic subjects after adjusting by age and sex (data not shown).

    The empirical power of the study calculated by bootstrapping ranged from low levels for vitamin E (12%, 95% confidence interval 9–16) to moderate levels for vitamin C (42%, 95% confidence interval 36–46).

    Biochemical measurements

    There were no differences in plasma/serum levels in any of the micronutrients/antioxidants between healthy subjects and asthmatics (Tables 5 and 6). Nor were any differences found between asthma groups as regards severity in the biochemical measurements, except in platelet GSH-Px activity (ANOVA, P<0.05), which was significantly lower in the most severe groups (groups 3 and 4).

    Table 5. Plasma/serum values in patients and controls. Results are presented as mean±SEM. ANOVA adjusted for sex and age

    Patients
    Controls
    P

    Magnesium (mg/dl) 2.0±1.2   2.0±1.1   NS
    Zinc (mg/dl) 78±16    80±13    NS
    Selenium (μg/dl) 79.0±1.1  77.5±2.7  NS
    Vitamin A (μg/dl) 73±25    72±24    NS
    Vitamin C (μmol/l) 54±17    58±19    NS
    Vitamin E (μmol/l)   28±7     29±7   NS
    Vitamin E/Chol (mmol/mg) 0.13±0.01 0.14±0.01 NS
    GSH-Px (mU/109 platelets) 156.9±5.2 145.4±6.2 NS
    Table 6. Plasma/serum values in patients according to disease severity. Mean±SEM

    Severity

    1
    2
    3
    4
    P

    * Groups 1 and 2 vs 3 and 4. ANOVA adjusted for sex and age.

    n 30 40 24 24
    Magnesium (mg/dl) 2.0±0.2 2.0±0.2 2.0±0.1 2.0±0.2 NS
    Zinc (mg/dl) 84.0±14 77.0±18 77.0±16 75.0±11 NS
    Selenium (μg/dl) 77.5±2.7 76.5±2.2 77.1±3.1 79.9±3.1 NS
    Retinol (vitamin A) (μg/dl) 82.0±23 76.0±19 77.0±27 75.0±33 NS
    Vitamin C (mmol/l) 53.0±16 53.0±6 55.0±17 50.0±25 NS
    Vitamin E (mmol/l) 26.0±7 28.0±6 29.0±9 30.0±8 NS
    GSH-Px (mU/109 platelets) 162.5±9.3 152.7±11.1 125.0±13.4 122.5±16 0.03*

    Aspirin-intolerant patients did not show any signifi-cant difference in micronutrients/antioxidants, either in dietary intake or biochemical measurements, in comparison with aspirin-tolerant patients.

    Correlations between food frequency questionnaire and biochemical measures

    Correlation between vitamin C intake and blood levels was statistically significant between crude values (r=0.47, P<0.001). After adjustment by total energy intake, the correlation coefficient between vitamin C intake and blood levels was 0.099 (95% confidence intervals, 0.067–0.131). This means that the relationship between vitamin C intake and blood levels was 1/100 (for each 100 units of ingested vitamin C, the blood level increased by 1 unit). No correlation was found between dietary values (crude and total energy adjusted) and biochemical measures of α-tocopherol, retinol, selenium, magnesium, and zinc.

    Jump to…

    Discussion

    1. We investigated differences in dietary micronutrient/antioxidant intake between asthmatics and nonasthmatics. Only patients with clearly defined asthma and with diets not compromised by food supplementation or avoidance were included. The usual dietary intake was measured by an FFQ. FFQs have been found to relate well to more detailed methods of dietary evaluation (21).
    The FFQ-estimated intake of vitamin C was correlated with blood concentration (r=0.47). However, we did not find any correlation between dietary nutrient intake and biochemical measurements with the other tested micronutrients/antioxidants. This is in keeping with previous studies, which have generally shown little or no correlation between dietary intake evaluation and biochemical quantification of these micronutrients/antioxidants (21, 23). Significant correlations are more often found in studies in which at least some of the recruited subjects are on supplemented diets (23). However, in our study, these subjects were excluded. Moreover, there are two reasons to explain why plasma/serum levels of micronutrients/antioxidants may not be correlated with dietary intake:

    · a single plasma/serum measurement of a micronutrient may be a poor marker of long-term intake detected by FFQ
    · plasma/serum levels of some micronutrients/antioxidants do not always reflect the level of their stores (liver, skeleton, and kidney).
    We found no evidence of any association between either dietary intake or plasma/serum levels of micronutrients/antioxidants and asthma. Nor did we find evidence that the severity of the disease has any influence on the plasma/serum levels of these substances.

    According to our results, no relationship exists between asthma and retinol intake. Troisi et al. (24) found that vitamin E may have a modest effect on the incidence of asthma. We did not find any difference in either vitamin E intake or serum levels between asthma patients and nonasthmatic controls.

    Some studies have reported short-term effects of vitamin C in the bronchoprovocation test and improvements in the lung-function test (25), but a beneficial effect of vitamin C was not detected in other studies (26). Olusi et al. (27) and Aderele et al. (28) found significantly higher plasma concentrations of vitamin C in controls than in asthma patients. However, no relationship was detected between vitamin C levels and asthma severity. In contrast, Troisi et al. (24) found no relationship between vitamin C intake and the subsequent development of asthma in women. Nor could Cook et al. (29) find any relationship between plasma vitamin C levels and wheezing.

    Selenium is an essential component of glutathione peroxidase

    Selenium is an essential component of glutathione peroxidase (GSH-Px), which reduces hydrogen peroxidase and other organic peroxides to nontoxic substances. Studies performed to determine a possible relationship between selenium levels and asthma have yielded contradictory results. Stone et al. (13) found that patients with asthma have lower concentrations of selenium in plasma and whole blood, but not in platelets, than controls. However, there was no concomitant reduction in GSH-Px activity in whole blood or platelets. In contrast, Flatt et al. (10) found that in whole blood, but not in plasma, selenium concentration and GSH-Px activity were lower in asthmatics than in healthy subjects. Similarly, reduced platelet GSH-Px activity was found by Misso et al. (11) in patients with asthma. Pearson et al. (12) found that aspirin-tolerant asthmatics had higher serum selenium concentrations than either aspirin-intolerant patients or control subjects. However, only aspirin-intolerant patients with asthma were found to have reduced platelet GSH-Px activity. In contrast, Plaza et al. (20) could not find any significant difference between platelet GSH-Px activity in aspirin-intolerant asthmatics and that in either aspirin-tolerant patients or healthy subjects. It has been suggested that GSH-Px levels may reflect the intensity of the inflammatory activity in asthma. Bibi et al. (30) demonstrated a close correlation between asthma severity and erythrocyte GSH-Px activity. Similarly, Pearson & Suarez-Mendez (31) also observed that platelet GSH-Px activity was lower in patients with severe asthma than in those with mild asthma. In keeping with this study, we found that platelet GSH-Px activity was significantly lower in patients with the most severe asthma. Since all these studies were cross-sectional, they could not determine whether the low platelet GSH-Px activity is responsible for asthma severity or is merely the consequence of an increased consumption of antioxidants in patients with a more active inflammatory process. In any case, the restoration of normal GSH-Px activity by increasing selenium intake might be a therapeutic alternative in asthma. Hasselmark et al. (32) found that selenium supplementation improved clinical symptoms in asthma patients, suggesting that the restoration of GSH-Px may improve control of bronchial inflammation.

    Although Britton et al. (33) found that dietary intake of magnesium was related to lung function, airway hyperreactivity, and self-reported wheezing in the gen-eral population, we could not find any difference, either in dietary intake or magnesium serum levels, between patients and healthy subjects. Like us, de Valk et al. (34), and Falker et al. (35) did not find any magnesium deficiency in asthmatics with respect to nonasthmatics, nor did the severity of the disease correlate with serum magnesium levels (35).

    The statistical power of our study was low to moder-ate (20–40%). Therefore, the lack of statistically signifi-cant differences in micronutrient/antioxidant intake between asthma and controls may have resulted from the study's being underpowered, resulting in a type 1 error.

    The possible relationship between asthma and dietary intake of micronutients has been deduced from studies which investigated the prevalence of wheezing (3, 4, 8, 33) or the presence of bronchial hyperresponsiveness (5). However, up to 10% of normal subjects are hyper-responsive to bronchoconstrictor stimuli, and wheezing is more prevalent than asthma in the general population (36).

    A reduced intake of vitamins A, E, or C is associated with an increased level of airflow obstruction (6–9). Since subjects with nonasthmatic airflow limitation demonstrate histamine or methacholine airway hyperresponsiveness (37), it may well be that a reduced vita-mins A, E, or C intake may predispose to bronchial hyperresponsiveness, simply by reducing airway diameter rather than by inducing asthma.

    If the important question is to know whether or not changes in the diet are associated with asthma, it seems more logical to investigate the relationship of diet and asthma than the association of dietary intake and indicators of asthma such as wheezing and hyperresponsiveness.

    In summary, we could not find any association bet-ween micronutrient/antioxidant intake or plasma/serum levels of micronutrients/antioxidants and asthma. Re-duction of platelet GSH-Px activity in the most severe patients suggests that their capacity to restore part of the antioxidant defences is diminished.

    Acknowledgments

    This study was supported by grants from Fondo de Investigaciones Sanitarias (FIS-92/698 and 94/337), Sociedad Española de Neumo-logía y Cirugía Torácica (SEPAR), and CIRIT (1998GR-00112). J.M. was supported in part by a grant from Ministerio de Educación y Ciencia (Spain).

    References

    1.
    · 1
    Monteleone CA, Sherman AR. Nutrition and asthma. Arch Intern Med 1997;157:23–34.

    o CrossRef,
    o PubMed,
    o CAS,
    o Web of Science®
    · 2
    Hatch GE. Asthma, inhaled oxidants, and dietary antioxidants. Am J Clin Nutr 1995;61 Suppl 3:625S–630S.

    · 3
    Schwartz J, Weiss ST. Dietary factors and their relationship to respiratory symptoms: the second National Health and Nutrition Examination Survey. Am J Epidemiol 1990;132:67–76.

    o PubMed,
    o Web of Science®
    · 4
    Bodner G, Godden D, Brown K, Little J, Ross S, Seaton A. Antioxidant intake and adult-onset wheeze: a case-control study. Eur Respir J 1999;13:22–30.

    o CrossRef,
    o PubMed,
    o Web of Science®
    · 5
    Soutar A, Seaton A, Brown K. Bronchial reactivity and dietary antioxidants. Thorax 1997;52:166–170.

    o CrossRef,
    o PubMed,
    o Web of Science®
    · 6
    Britton JR, Pavord ID, Richards HA, et al. Dietary antioxidant vitamin intake and lung function in the general population. Am J Respir Crit Care Med 1995;151:1383–1387.

    o PubMed,
    o CAS,
    o Web of Science®
    · 7
    Schwartz J, Weiss ST. The relationship of dietary vitamin C intake to level of pulmonary function in the First National Health and Nutrition Survey (NHANES I). Am J Clin Nutr 1994;59: :110–114.

    o PubMed,
    o Web of Science® Times Cited: 133
    · 8
    Dow L, Tracey M, Villar A, et al. Does dietary intake of vitamins C and E influence lung function in older people? Am J Respir Crit Care Med 1996;154:1401–1404.

    o PubMed,
    o CAS,
    o Web of Science®
    · 9
    Morabia A, Serenson A, Kumanyiki S, et al. Vitamin A, cigarette smoking and airway obstruction. Am J Respir Crit Care Med 1989;140:1312–1316.

    o PubMed,
    o Web of Science® Times Cited: 65
    · 10
    Flatt A, Pearce N, Thomson CD, Sears MR, Robinson MF, Beasley R. Reduced selenium in asthmatic subjects in New Zealand. Thorax 1990;45:95–99.

    o CrossRef,
    o PubMed,
    o CAS,
    o Web of Science®
    · 11
    Misso NL, Powers KA, Gillon RL, Stwart GA, Thompson PJ. Reduced platelet glutathione peroxidase activity and serum selenium concentration in atopic asthmatic patients. Clin Exp Allergy 1996;26:838–847.

    Direct Link:

    o Abstract
    o PDF(4585K)
    o References
    · 12
    Pearson DJ, Suarez-Mendez VJ, Day JP, Miller PF. Selenium status in relation to reduced glutathione peroxidase activity in aspirin-sensitive asthma. Clin Exp Allergy 1991;21:203–208.

    Direct Link:

    o Abstract
    o PDF(2572K)
    o References
    · 13
    Stone J, Hinks LJ, Beasley R, Holgate ST, Clayton BA. Reduced selenium status of patients with asthma. Clin Sci 1989;77:495–500.

    o PubMed,
    o CAS,
    o Web of Science®
    · 14
    Picado C, Deulofeu R, Lleonart R, et al. Lipid and protein metabolism in asthma. Effects of diet and cortico-steroid therapy. Allergy 1999;55:569–575.

    Direct Link:

    o Abstract
    o Full Article (HTML)
    o PDF(86K)
    o References
    · 15
    Global Initiative for Asthma. Global strategy for asthma management and prevention. NHLBI/WHO workshop. National Institutes of Health, National Heart, Lung and Blood Institute 1995, Publication no. 95;3659:1–176.

    · 16
    Shearer MJ. Vitamin E. In: CK LIM, editor. HPLC of small molecules. London: Oxford University Press, 1986: 177–182.

    · 17
    Catigiani GL, Bieri JG. Measurement of serum retinol by high performance liquid chromatography. Clin Chem 1983;29:708–712.

    o PubMed,
    o Web of Science® Times Cited: 474
    · 18
    Speek AJ, Schrijver J, Schreurs WHP. Measurement of total ascorbic acid in biological fluids. J Chromatogr 1984;305:53–59.

    o CrossRef,
    o PubMed,
    o Web of Science® Times Cited: 149
    · 19
    Van Cauwenberg R, Robberecht H, Van Dael P, Deelstra H. Direct selenium determination in human whole blood by graphite furnace atomic absorption spectrometry with deuterium correction using a L'vov platform, a Pd/Mg matrix modification and appropriate dilution. J Trace Elem Electrolytes Health Dis 1990;4:127–131.

    o PubMed,
    o Web of Science® Times Cited: 21
    · 20
    Plaza V, Prat J, Rossello J, et al. In vitro release of arachidonic acid metabolites, glutathione peroxidase, and oxygen-free radicals from platelets of asthmatic patients with and without aspirin intolerance. Thorax 1995;50:490–496.

    o CrossRef,
    o PubMed,
    o CAS,
    o Web of Science®
    · 21
    Willett WC. Nutritional epidemiology. New York: Oxford University Press, 1990.

    · 22
    Bradly E, Tibshirani RJ. An introduction to Bootstrap. New York: Chapman & Hall, 1993.

    · 23
    Jacques PF, Sulsky SI, Sadowski JA, Phillips JCC, Rush D, Willett WC. Comparison of micronutrient intake measured by a dietary questionnaire and biochemical indicators of micro-nutrient status. Am J Clin Nutr 1993;57:182–189.

    o PubMed,
    o CAS,
    o Web of Science®
    · 24
    Troisi RJ, Willett WC, Weiss ST, Trichopoulos D, Rosner B, Speizer FE. A prospective study of diet and adult-onset asthma. Am J Respir Crit Care Med 1995;151:1401–1408.

    o PubMed,
    o CAS,
    o Web of Science®
    · 25
    Cohen HA, Neuman I, Nahum H. Blocking effect of vitamin C in exercise-induced asthma. Arch Pediatr Adolesc Med 1997;151:367–370.

    o PubMed,
    o CAS,
    o Web of Science®
    · 26
    Malo JL, Cartier A. Lack of acute effects of ascorbic acid on spirometry and airway responsiveness to histamine in subjects with asthma. J Allergy Clin Immunol 1986;78:1153–1158.

    o CrossRef,
    o PubMed,
    o CAS,
    o Web of Science®
    · 27
    Olusi SO, Ojutiku OO, Jessop WJE, Iboko MI. Plasma and white blood cell ascorbic acid concentrations in patients with bronchial asthma. Clin Chim Acta 1979;92:161–166.

    o CrossRef,
    o PubMed,
    o CAS,
    o Web of Science®
    · 28
    Aderele WR, Ette SI, Oduwoule O, Ikpeme SJ. Plasma vitamin C (ascorbic acid) levels in asthmatic children. Afr J Med Sci 1985;14:115–120.

    o CAS
    · 29
    Cook DG, Carey IM, Whincup PH, et al. Effect of fresh fruit consumption on lung function and wheeze in children. Thorax 1997;52:628–633.

    o CrossRef,
    o PubMed,
    o CAS,
    o Web of Science®
    · 30
    Bibi H, Schlesinger M, Tabachnik E, Schwartz Y, Iscovitz H, Iaina A. Erythrocyte glutathione peroxidase activity in asthmatic children. Ann Allergy 1988;61:339–340.

    o PubMed,
    o CAS,
    o Web of Science® Times Cited: 25
    · 31
    Pearson J, Suarez-Mendez J. Abnormal platelet hydrogen peroxide metabolism in aspirin hypersensitivity. Clin Exp Allergy 1990;20:157–163.

    Direct Link:

    o Abstract
    o PDF(3082K)
    o References
    · 32
    Hasselmark L, Malmgren R, Zetterström O, Unge G. Selenium supplementation in intrinsic asthma. Allergy 1993;48:30–36.

    o PubMed,
    o CAS,
    o Web of Science®
    · 33
    Britton J, Pavord I, Wisniewski A, et al. Dietary magnesium, lung function, wheezing, and airway hyperreactivity in a random adult population. Lancet 1994;344:357–362.

    o CrossRef,
    o PubMed,
    o Web of Science®
    · 34
    De Valk HW, Kok PT, Struyvenberg A, et al. Extracellular and intracellular magnesium concentrations in asthmatic patients. Eur Respir J 1993;6:1122–1125.

    o PubMed,
    o CAS,
    o Web of Science® Times Cited: 25
    · 35
    Falker D, Glauser J, Allen M. Serum magnesium levels in asthmatic patients during acute exacerbations of asthma. Am J Emerg Med 1992;10:1–3.

    o CrossRef,
    o PubMed,
    o Web of Science® Times Cited: 21
    · 36
    Cockcroft DW. Airway hyper-responsiveness. Relevance of random population data to clinical usefulness. Am Rev Respir Dis 1990;142:497–500.

    o PubMed,
    o CAS,
    o Web of Science® Times Cited: 87
    · 37
    Ramsdale EH, Morris MM, Roberts RS, Hargrave FE. Bronchial responsiveness to methacholine in chronic bronchitis: relationship to airflow obstruction and cold air responsiveness. Thorax 1984;39:912–918.

    o CrossRef,
    o PubMed,
    o Web of Science®
    Get PDF (82K)

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    Aborto: Dinheiro de Sangue. Por que sua “legalização” é tão importante no Brasil?

    Colheita Fetal

    Pela primeira vez, ouvir um informante revela como os bebês (às vezes ao vivo) são colhidas a partir de clínicas de aborto para revenda. Cortesia da dinâmica da vida.

    Você já se perguntou o que as clínicas de aborto fazem dos bebês abortados? Você já se perguntou como essas clínicas ganham dinheiro extra? Você já se perguntou por que pró-abortistas insistem em manter o procedimento de aborto de nascimento parcial legal?Artigos recentes sobre colheita Fetal
    Julho 1999

    Peças do bebê à venda
    Um lote de olhos pela UPS – 30 fígados por FedEx

    Por J. C. Willke, MD

    Depois de lutar contra o aborto há 30 anos eu pensei que tinha visto e ouvido tudo, mas não é assim.

    Baby Parts for Sale. Recent Articles on Fetal Harvesting

    Sign Up for Free Pro-Life News From LifeNews.com

    http://www.lifenews.com/2010/05/20/state-5108/

    Abortion in U.S. a $1 billion industry: study
    May 4th, 2010
    By Rick DelVecchio
    Abortion in the United States has become a $1 billion-a-year industry quietly fostered over 40 years by a climate that is allowing related, morally suspect commercial offshoots to develop in pharmaceuticals, cosmetics and life sciences, a new study alleges.

    […] A Cura e prevenção ocorrem por terapia natural. Suplementação de vitaminas, dieta alimentar […]

    Você já se perguntou o que as clínicas de aborto fazem dos bebês abortados? Você já se perguntou como essas clínicas ganham dinheiro extra? Você já se perguntou por que pró-abortistas insistem em manter o procedimento de aborto de nascimento parcial legal?

    Ever wonder what abortion clinics do with aborted babies? Ever wonder how the clinics make extra money? Ever wonder why pro-abortionists insist on keeping the Partial-birth abortion procedure legal?
    Fetal Harvesting

    Aborto: Dinheiro de Sangue. Por que sua “legalização” é tão importante no Brasil?
    06/11/2010 — Celso Galli Coimbra

    Aborto: Dinheiro de Sangue. Por que sua “legalização” é tão importante no Brasil?

    Colheita Fetal

    Pela primeira vez, ouvir um informante revela como os bebês (às vezes ao vivo) são colhidas a partir de clínicas de aborto para revenda. Cortesia da dinâmica da vida.

    Você já se perguntou o que as clínicas de aborto fazem dos bebês abortados? Você já se perguntou como essas clínicas ganham dinheiro extra? Você já se perguntou por que pró-abortistas insistem em manter o procedimento de aborto de nascimento parcial legal?Artigos recentes sobre colheita Fetal
    Julho 1999

    Peças do bebê à venda
    Um lote de olhos pela UPS – 30 fígados por FedEx

    Por J. C. Willke, MD

    Depois de lutar contra o aborto há 30 anos eu pensei que tinha visto e ouvido tudo, mas não é assim.

    Baby Parts for Sale. Recent Articles on Fetal Harvesting

    Sign Up for Free Pro-Life News From LifeNews.com

    http://www.lifenews.com/2010/05/20/state-5108/

    Abortion in U.S. a $1 billion industry: study
    May 4th, 2010
    By Rick DelVecchio
    Abortion in the United States has become a $1 billion-a-year industry quietly fostered over 40 years by a climate that is allowing related, morally suspect commercial offshoots to develop in pharmaceuticals, cosmetics and life sciences, a new study alleges.

  5. […] A Cura e prevenção ocorrem por terapia natural. Suplementação de vitaminas, dieta alimentar […]

    Referencias Médico-Científicas Sobre Tratamento, Cura e Prevenção, doenças neurodegenerativas e autoimunes. Vitamina D.

    Vitamina D pode revolucionar o tratamento da esclerose múltipla*
    http://biodireitomedicina.wordpress.com/category/doencas-autoimunes/

    POR UM NOVO PARADIGMA DE CONDUTA E TRATAMENTO
    http://www.institutodeautoimunidade.org.br/novo-paradigma.html

    Por Dr. Cícero Galli Coimbra
    Médico Internista e Neurologista
    Professor Associado Livre-Docente da Universidade Federal de São Paulo
    Presidente do Instituto de Investigação e Tratamento de Autoimunidade


    O vídeo referido na reportagem dominical de 27.05.12 da Folha está no endereço:
    Vitamina D – Por uma outra terapia (Vitamin D – For an alternative therapy)

    Folha de São Paulo: Terapia polêmica usa vitamina D em doses altas contra esclerose múltipla


    Vitamina D pode revolucionar o tratamento da esclerose múltipla

    Vitamina D pode revolucionar o tratamento da esclerose múltipla


    Taxas baixas de vitamina D na maioria da população preocupam especialistas

    Taxas baixas de vitamina D na maioria da população preocupam especialistas

    Pediatras dobram recomendação de consumo diário de vitamina D

    Pediatras dobram recomendação de consumo diário de vitamina D

    Doses diárias de Sol – nos horários certos e com os devidos cuidados

    Doses diárias de Sol – nos horários certos e com os devidos cuidados

    “(…) cerca de 70% da população mundial apresenta taxas inadequadas de vitamina D, substância que, dentro do corpo, trabalha como um hormônio. O fenômeno da insuficiência não poupa nem países tropicais, como o Brasil, e a defasagem tende a ser maior nas grandes cidades, já que, dentro de casa, no carro ou no escritório, as pessoas acabam fugindo do sol. De acordo com o endocrinologista Geraldo Santana, do Instituto Mineiro de Endocrinologia, “a deficiência de vitamina D é um achado frequente e também preocupante devido à importante ação da substância no organismo.”
    Celso Galli Coimbra
    OABRS 11352
    cgcoimbra@gmail.com
    Em 19.06.2012
    __

    Vitamina D: A Desinformação Médica e o Direito à Informação do Cidadão

    Vitamina D: A Desinformação Médica e o Direito à Informação do Cidadão

    Vitamina D pode combater males que mais matam pessoas no mundo

    Vitamina D pode combater males que mais matam pessoas no mundo

    Informações médicas sobre a prevenção e tratamento de doenças neurodegenerativas e autoimunes, Parkinson, Alzheimer, Lupus, Psoríase, Vitiligo, como depressão

    Informações médicas sobre a prevenção e tratamento de doenças neurodegenerativas e autoimunes, como Parkinson, Alzheimer, Lupus, Psoríase, Vitiligo, depressão

    Vitamina D é importantíssima para a saúde
    ”Estudos realizados no Brasil e no exterior apontam a importância da substância na prevenção e no tratamento do câncer, diabetes e de doenças neurológicas, cardiovasculares e até degenerativas, como a esclerose múltipla.”

    Vitamina D é importantíssima para a saúde


    A importância da colina para a regeneração neuronal

    A importância da colina para a regeneração neuronal


    “A colina é especialmente importante na gravidez. “Vários estudos já mostraram que ela é tão ou mais importante do que o ácido fólico durante a gestação”
    Antes inimigo da saúde cardiovascular, o alimento agora está liberado pelos médicos

    O tratamento com vitamina D deve ser feito com indicação por médico atualizado

    O tratamento com vitamina D deve ser feito com indicação por médico atualizado

    Taxas baixas de vitamina D na maioria da população preocupam especialistas

    Taxas baixas de vitamina D na maioria da população preocupam especialistas


    Solução que vem do sol – com os devidos cuidados

    Solução que vem do sol – com os devidos cuidados

    11 de junho de 2012
    “A vitamina D, que precisa dos raios solares para ser sintetizada no corpo, é a base de uma alternativa revolucionária para tratar doenças autoimunes”

    Informações médicas sobre a prevenção e tratamento de doenças neurodegenerativas e autoimunes, como Parkinson, Alzheimer, Lupus, Psoríase, Vitiligo, depressão
    Entrevista em TV com o Dr. Cícero Galli Coimbra, professor neurologista da Universidade Federal de São Paulo – Unifesp.

    Informações médicas sobre a prevenção e tratamento de doenças neurodegenerativas e autoimunes, como Parkinson, Alzheimer, Lupus, Psoríase, Vitiligo, depressão


    Vitamina D pode revolucionar o tratamento da esclerose múltipla

    Vitamina D pode revolucionar o tratamento da esclerose múltipla


    Sobre este assunto, assista: Vitamina D – por uma outra terapia

    Vitamina D – Por uma outra terapia

    Informações médicas sobre a prevenção e tratamento de doenças neurodegenerativas e autoimunes, como Parkinson, Alzheimer, Lupus, Psoríase, Vitiligo, depressão


    —-

    Vitamina D e cálcio juntos podem aumentar expectativa de vida de idosos

    “VITAMINA D
    Também chamada calciferol, a vitamina D promove a absorção do cálcio pelo organismo após a exposição solar. 90% da vitamina D que precisamos vem da exposição ao sol. A deficiência da vitamina pode provocar raquitismo, alterações no crescimento e nos ossos, além de reduzir a imunidade. A vitamina D está relacionada ainda ao bom funcionamento do coração, do cérebro e da secreção de insulina pelo pâncreas. A presença significativa da substância é vista em poucos alimentos, como fígado, óleos de peixes gordurosos e gema de ovo.”

    Vitamina D e cálcio juntos podem aumentar expectativa de vida de idosos

    Vitamina D pode combater males que mais matam pessoas no mundo

    Vitamina D pode combater males que mais matam pessoas no mundo

    —-

  6. […] A Cura e prevenção ocorrem por terapia natural. Suplementação de vitaminas, dieta alimentar […]

    Vitamina D: solução para doenças autoimunitárias e neurodegenerativas
    16/07/2012 — Celso Galli Coimbra

    Vitamina D: solução para doenças autoimunitárias e neurodegenerativas

    Alois Alzheimer ca. 1910 (Photo credit: Wikipedia)
    Sobre este assunto, assista:
    Vitamina D – Sem Censura – Dr. Cicero Galli Coimbra e Daniel Cunha

    Vitamina D – Sem Censura – Dr. Cicero Galli Coimbra e Daniel Cunha

    Vitamina D – Por uma outra terapia (Vitamin D – For an alternative therapy)

    Informações médicas sobre a prevenção e tratamento de doenças neurodegenerativas

    Leia:
    Vitamina D pode revolucionar o tratamento da esclerose múltipla

    Vitamina D pode revolucionar o tratamento da esclerose múltipla


    __
    Estudos revelam e casos clínicos comprovam que nutriente é fundamental para prevenção e controle eficaz de moléstias graves – 16/07/2010 16:50 (Elizângela Isaque – Da equipe Medicando)

    A sabedoria popular nos ensina que é sempre melhor prevenir do que remediar. Felizmente, em algumas circunstâncias, especificamente nas ligadas à saúde, a forma de prevenção é a mesma que proporciona a cura ou, no mínimo, um controle eficaz de determinados problemas. Esse é o caso da vitamina D, substância que tem sido fonte de constantes estudos e de importantes descobertas, no que se refere às doenças autoimunitárias e neurodegenerativas, como esclerose múltipla, depressão, artrite reumatóide, Parkinson, mal de Alzheimer, lúpus e vitiligo, entre outras.

    De acordo com a literatura médica clássica, a vitamina D exerce um papel fundamental para a manutenção do equilíbrio de determinadas funções do organismo humano, como a inibição de problemas como o raquitismo em crianças e a osteoporose em adultos. Entretanto, de acordo com as novas descobertas, as doses diárias recomendadas até hoje, de 400 UI (Unidades Internacionais), que equivale a um micrograma, estão longe do ideal necessário para prevenir, estabilizar ou mesmo anular sintomas relacionados à carência dessa substância.

    Embora alguns alimentos sejam fonte de vitamina D, a forma natural mais eficiente de obtê-la é por meio da exposição diária ao sol. “Cerca de 10 minutos, todos os dias, com 90% do corpo exposto ao sol matinal, é suficiente para que maioria das pessoas obtenha a quantidade aproximada de 20.000 UI”, explica o neurologista e professor do Departamento de Neurologia e Neurocirurgia da Universidade Federal de São Paulo (UNIFESP) Dr. Cícero Galli Coimbra.

    No entanto, Dr. Cícero lembra que algumas pessoas apresentam maior dificuldade de transformar em ativa a forma da vitamina D produzida pela exposição solar, devido às particularidades de cada organismo. Devido a essas características, alguns indivíduos, mesmo com hábitos que os exponham diariamente ao sol, podem apresentar deficiência desta substância e, consequentemente, desenvolverem algum problema proveniente dessa carência. Por isso, o médico recomenda a ingestão diária da vitamina D em forma de cápsula ou gotas, em pessoas portadoras dessa característica genética, ou que tenham uma rotina diária caracterizada por baixa exposição solar.
    – –

  7. […] A Cura e prevenção ocorrem por terapia natural. Suplementação de vitaminas, dieta alimentar […]

    deficiencia de vitamina D desregula a imunidade.

    A mais pura verdade, há milhares de artigos médico-científicos na internet e ainda as publicações de obras não indexadas, sobre a Cura e prevenção de doenças neurodegenerativas e autoimunes: Parkinson, Alzheimer, Lupus, Psoríase, Vitiligo, depressão, esclerose múltipla, câncer, artrite-reumatoide, diabetes, doenças cardiovasculares, diabetes, asma, infecções e todos os tipos de doenças. É a deficiencia da vitamina D no organismo que leva a essas doenças. Esta é a realidade do mundo moderno, o atual estilo de vida, a falta de tempo, pouca ou nenhuma exposição da pele ao sol, e a pandemia de doenças crônicas.

    Vitamina D – Sem Censura – Dr. Cicero Galli Coimbra e Daniel Cunha – 18.junho.2012

    “Estamos vivendo uma defasagem entre o conhecimento científico e a prática médica” – Dr. Cicero Galli Coimbra


    por que então inventaram de usar embriões humanos em ‘pesquisas’ e nos transplantes de células-tronco de fetos ?

    Porque a economia das doenças cronicas e dos transplantes é o negócio de alto consumo e de altíssimo lucro enquanto e até quando as pessoas, a população em geral, continuar sem informação e desprovida de terapia e tratamento efetivo para a cura.

    Os LUCROS

    Fundaram o CFEMEA, que não só conta com o apoio de organizações internacionais financiadoras da campanha do aborto, conta também com contribuições do governo federal – a Receita Federal deve saber explicar onde o poder executivo, a Presidencia da República e a Casa Civil fazem investimentos. Também financiam o CFEMEA – e vários outros grupos pró-aborto – a Fundação Ford, a Fundação Mac Arthur, o Fundo das Nações Unidas para a População (FNUAP) e o Fundo das Nações Unidas para a Mulher (UNIFEM). A BENFAM é a filial brasileira da maior empresa de abortamentos a norteamericana Planned Parenthood. O ganho da PP, em dinheiro, com os abortos.

    ABORTO: DINHEIRO DE SANGUE. POR QUE SUA “LEGALIZAÇÃO” É TÃO IMPORTANTE NO BRASIL?

    06/11/2010 — Celso Galli Coimbra

    Aborto: Dinheiro de Sangue. Por que sua “legalização” é tão importante no Brasil?

    A inconstitucionalidade da tramitação de legislação legalizadora do aborto no Brasil por Celso Galli Coimbra
    Dr. Celso Galli Coimbra Advogado OABRS 11352 disponível em: http://biodireitomedicina.wordpress.com/2008/11/22/a-inconstitucionalidade-da-tramitacao-de-legislacao-legalizadora-do-aborto-no-brasil/

    Planned Parenthood Federation of America (PPFA), a maior organização abortista do mundo.
    “A Planned Parenthood Federation of America (PPFA), a maior organização abortista do mundo, publicou seu relatório financeiro de julho de 2004 a junho de 2005, onde mostra que sua arrecadação total chega a quase 900 milhões de dólares. O relatório evita referir-se à quantidade de mulheres falecidas em suas clínicas como conseqüência dos abortos praticados legalmente, e falsamente oferecidos como “seguros”.”

    Journal of American Physicians and Surgeons: aborto é principal causador do câncer de mama. Celso Galli Coimbra – OABRS 11352

    Journal of American Physicians and Surgeons: aborto é principal causador do câncer de mama

    ABORTION IN U.S. A $1 BILLION INDUSTRY: STUDY
    Pro-Life News From LifeNews.com
    http://www.lifenews.com/2010/05/20/state-5108/


  8. […] A Cura e prevenção ocorrem por terapia natural. Suplementação de vitaminas, dieta alimentar […]

    Verdade, há milhares de artigos médico-científicos na internet e ainda as publicações de obras não indexadas, sobre a Cura e prevenção de doenças neurodegenerativas e autoimunes: Parkinson, Alzheimer, Lupus, Psoríase, Vitiligo, depressão, esclerose múltipla, câncer, artrite-reumatoide, diabetes, doenças cardiovasculares, diabetes, asma, infecções e todos os tipos de doenças. É a deficiencia da vitamina D no organismo que leva a essas doenças.Esta é a realidade do mundo moderno, o atual estilo de vida, a falta de tempo, pouca ou nenhuma exposição da pele ao sol, e a pandemia de doenças crônicas.

    —–

    Vitamina D – Sem Censura – Dr. Cicero Galli Coimbra e Daniel Cunha – 18.junho.2012

    “Estamos vivendo uma defasagem entre o conhecimento científico e a prática médica” – Dr. Cicero Galli Coimbra

    Neurodegeneraçao, Parkinson, Vitamina D

    Vitamina D – por uma outra terapia

    Vitamina D – Por uma outra terapia

    Vitamin D – For an alternative therapy

    The Real Story on Vitamin D

    __

    “Os medicamentos que curam completamente, não dão lucro”

    Fonte:

    Indústria farmacêutica – “Os medicamentos que curam completamente, não dão lucro”

    Entrevista com Dr. Richard J. Roberts, Prêmio Nobel da Medicina 1993

    ———————–

  9. […] industria farmaceutica e laboratórios multinacionais e clínicas – inclusive abortistas. https://objetodignidade.wordpress.com/2012/02/18/a-cura-e-prevencao-ocorrem-por-terapia-natural-suple&#8230;     Brasil, de 2002 a 2012 passa pela fase totalitária: ilegalidade e ilegitimidade são […]

  10. […] industria farmaceutica e laboratórios multinacionais e clínicas – inclusive abortistas. https://objetodignidade.wordpress.com/2012/02/18/a-cura-e-prevencao-ocorrem-por-terapia-natural-suple&#8230;     Brasil, de 2002 a 2012 passa pela fase totalitária: ilegalidade e ilegitimidade são […]

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